ABSTRACT
Soft tissue is defined as the complex of non epithelial extraskeletal structures of the body exclusive of the supportive tissue of the various organs and the hematopoietic/lymphoid tissue. It is composed of fibrous tissue, adipose tissue, skeletal muscle, blood and lymph vessels and peripheral nervous system. Soft tissue tumours constitute a large and heterogenous group of neoplasms. WHO has classified soft tissue tumors in different categories like Adipocytic tumors, Fibroblastic, Fibro-histiocytic, Smooth muscle, Pericytic, Skeletal muscle, Vascular, Chondro-osseous & tumors of uncertain differentiation. These are further subdivided into Bengin, Intermediate & Malignant. Pattern of a particular disease in any population is studied with the idea of obtaining information about the clinical presentation, the varied morphology and the etiological factors that can be assessed in relation to its prognosis. The present study was undertaken with a view to getting information about the rate of prevalence, relative frequency of various histopathological types of neoplasms and morphological patterns of soft tissue tumors in our institution.
ABSTRACT
Primary testicular lymphomas (PTL) are rare entities representing 1-2% of Non-Hodgkin's Lymphoma (NHL) and 1-7% of malignant testicular tumours. They are most commonly seen in men older than 60 years. The most common type of primary testicular lymphoma (PTL) is diffuse large B-cell type which has the potential for aggressive clinical behaviour. We report the case of a 45 years old male with primary testicular lymphoma which was first diagnosed on Fine Needle Aspiration Cytology (FNAC) and subsequently confirmed histopathologically and immunophenotypically as Diffuse Large B-Cell Lymphoma (DLBCL) showing CD20 positivity. This case report confirms the literature data concerning the rarity of testicular Non Hodgkin's Lymphoma (TNHL) with DLBCL being the most common phenotype and the poor prognosis of the disease despite aggressive management.
Subject(s)
Adult , Bone Neoplasms/diagnosis , Biopsy, Fine-Needle/methods , Calcaneus , Humans , Male , Osteosarcoma/diagnosisABSTRACT
Fine needle aspiration cytology (FNAC) is of particular relevance in head and neck lesions because of easy assessibility, excellent patient compliance, miminally invasive nature of procedure and helping to avoid surgery in non-neoplastic lesions, inflammatory conditions and also some tumors. The study was conducted on 160 patients presenting with non-thyroidal head and neck swellings. Swellings arising from lymphnodes formed largest group 110 (68.75%) cases, salivary gland origin leisions comprised of 15(9.3%) cases and miscellaneous lesions 35 (21.8%) patients. Aspiration was satisfactory in 153 (95.63%) and unsatisfactory in 7 (4.40%) patients. The cytodiagnostic yield was 147 (91.87%) cases in the study. In 46 patients surgical intervention and histopathological examination (HPE) of the specimen was undertaken. The sensitivity of FNAC compared with HPE where available in diagnosing lymphnode lesions was 83.33%, salivary gland lesions was 100% and miscellaneous swellings was 95.83%. The overall sensitivity in the study in diagnosing non-thyroidal head and neck lesion was 93.47%. No major complication was recorded.
ABSTRACT
Diagnostic Assessment of bone marrow aspirate particle smears, imprints and biopsy sections was done on 10 Non- Haematological disorders. Core needle biopsy of the bone marrow is a safe and useful procedure. It is a valuable diagnostic aid for measurement of marrow cellularity, metastatic tumours and fibrosis . Bilateral trephine biopsy was conducted wherever necessary. Touch imprints were useful for studying cell morphology, where aspiration yielded dry tap.All the three procedures of bone marrow aspiration, trephine biopsy and touch imprints were found to be complementary to each other and superiority of one method over the other depended on the specific disease process.
ABSTRACT
Diagnostic Assessment of bone marrow aspirate particle smears, imprints and biopsy sections was done on 40 haematological disorders. Core needle biopsy of the bone marrow is a safe and useful procedure. It is a valuable diagnostic aid for measurement of marrow cellularity and fibrosis.Bilateral trephine biopsy was conducted wherever necessary.Bone marrow aspiration was the most effective method for studying morphological details and was able to diagnose most of the cases except the 2 cases of myelofibrosis which yielded dry tap for which trephine biopsy was diagnostic.Trephine biopsy was also found to be superior for staging of lymphomas and to study the ALIP in MDS.Touch imprints were useful for studying cell morphology, where aspiration yielded dry tap.All the three procedures of bone marrow aspiration, trephine biopsy and touch imprints were found to be complementary to each other and superiority of one method over the other depended on the specific disease process.